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What is DHM? The ingredient doing the heavy lifting in Pregame

August 29, 2026

Ever heard of DHM? If not, you're about to. It's the reason Pregame exists.

What DHM actually is

Dihydromyricetin, DHM for short, is a plant-based flavonoid extracted from the Japanese raisin tree (Hovenia dulcis). That tree has been used in traditional East Asian wellness practices for centuries. Scientists started paying closer attention to it over the last couple of decades, and what they found was interesting enough to build a company around.

DHM works in two ways that matter for people who drink.

First, it supports your liver's ability to metabolize alcohol. Your liver uses enzymes, specifically alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), to break down alcohol and its byproduct, acetaldehyde. Acetaldehyde is the stuff that makes you feel rough the next morning. DHM supports those enzyme processes, which means your body can do its job better while you're drinking and in the hours after.

Second, DHM has antioxidant properties. Alcohol consumption generates oxidative stress: it throws off your body's natural balance. Antioxidants help restore it. DHM pitches in on that front too.

The research behind DHM is real. UCLA published a study in 2012 showing it reduced alcohol's effects in preclinical models. More work has followed since. We're not making medical claims here. DHM is a dietary supplement, and supplements don't treat or prevent disease. But the mechanism is legitimate, and that's why it's in serious formulas.

Why Pregame chose DHM

We built Pregame around one question: what does your body actually need when you drink?

The answer isn't a mystery. Alcohol taxes your liver, depletes B vitamins, disrupts electrolyte balance, and generates oxidative stress. So we put together ingredients that address each of those things, and DHM handles the biggest one.

We didn't stop at DHM, though. DHM supports liver enzyme function. But NAC (N-Acetyl Cysteine) is a precursor to glutathione, your body's primary antioxidant, which alcohol depletes heavily. DHM and NAC together cover more ground than either one alone.

That's the thinking behind the whole formula: nothing is there by accident, nothing is redundant, and everything is listed on the label with a plain-English explanation of why it's there.

What makes Pregame different

A lot of "recovery" products are basically vitamin packs with a marketing refresh. B vitamins, vitamin C, maybe some electrolytes. Fine, but incomplete.

Pregame has those too. Every bottle has a full B-vitamin complex (B1, B2, B3, B6, B12), electrolytes (sodium, potassium, magnesium), and vitamin C. But the formula leads with DHM and NAC because that's where the real support happens.

We also included:

Nine ingredients. Nothing hidden.

One honest note

Pregame is a dietary supplement, not a medication. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. It also won't counteract impairment: don't drink and drive, don't drink past your limit, drink responsibly.

What Pregame does: it supports antioxidant function, liver health, and hydration, and it helps you feel like yourself the morning after a night out. That's the honest version.

Want the full ingredient list with the reason each one is in the formula? It's all on the formula page.

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